\n
\n\tBeyin her g\u00fcn say\u0131s\u0131z g\u00f6r\u00fcnt\u00fc ve deneyimi kaydediyor ancak bunlar\u0131n yaln\u0131zca k\u00fc\u00e7\u00fck bir k\u0131sm\u0131 kal\u0131c\u0131 an\u0131lara d\u00f6n\u00fc\u015f\u00fcyor.<\/p>\n
\n\tBilim insanlar\u0131, neyin hat\u0131rlanaca\u011f\u0131n\u0131 tahmin etmeye yard\u0131mc\u0131 olan bir sinirsel aktivite \u00f6r\u00fcnt\u00fcs\u00fc tespit ederek geleneksel olarak duygular ve korkuyla ili\u015fkilendirilen bir beyin b\u00f6lgesinin \u00e7ok daha geni\u015f bir i\u015flevi oldu\u011funa i\u015faret etti.<\/p>\n
\n\tCedars-Sinai Sa\u011fl\u0131k Bilimleri \u00dcniversitesindeki ara\u015ft\u0131rmac\u0131lar taraf\u0131ndan yap\u0131lan ve Nature Neuroscience dergisinde yay\u0131mlanan ke\u015fif, temporal lobun derinliklerinde yer alan ceviz b\u00fcy\u00fckl\u00fc\u011f\u00fcndeki amigdala yap\u0131s\u0131na odaklan\u0131yor.<\/p>\n
\n\tBulgular, bu b\u00f6lgedeki \u00f6zelle\u015fmi\u015f n\u00f6ronlar\u0131n uzun s\u00fcreli haf\u0131zada depolanmak \u00fczere hangi yeni deneyimlerin se\u00e7ilece\u011fini belirlemeye yard\u0131mc\u0131 oldu\u011funu g\u00f6steriyor.<\/p>\n
\n\tAmigdala kal\u0131c\u0131 an\u0131lar\u0131n se\u00e7ilmesine nas\u0131l yard\u0131mc\u0131 oluyor?<\/h2>\n
\n\tAmigdalan\u0131n \u00f6zellikle korkunun i\u015flenmesi olmak \u00fczere duygusal ve sosyal davran\u0131\u015flardaki rol\u00fc uzun s\u00fcredir biliniyor. Haf\u0131zaya katk\u0131s\u0131n\u0131n ise genellikle duygusal a\u00e7\u0131dan \u00f6nem ta\u015f\u0131yan deneyimlere odakland\u0131\u011f\u0131 d\u00fc\u015f\u00fcn\u00fcl\u00fcyordu. Yeni ara\u015ft\u0131rma, bu yap\u0131n\u0131n etkisinin belirgin bir duygusal bile\u015feni olmayan daha s\u0131radan g\u00f6rsel deneyimleri de kapsayacak \u015fekilde geni\u015fledi\u011fini g\u00f6steriyor.<\/p>\n
\n\tAra\u015ft\u0131rmac\u0131lar y\u00fczler, hayvanlar ve manzaralar dahil olmak \u00fczere belirli g\u00f6r\u00fcnt\u00fc t\u00fcrlerine \u00f6ncelikli olarak tepki veren n\u00f6ronlar tespit etti. Bu n\u00f6ronlar tercih ettikleri kategorideki bir g\u00f6r\u00fcnt\u00fcye daha g\u00fc\u00e7l\u00fc tepki verdi\u011finde, kat\u0131l\u0131mc\u0131lar\u0131n s\u00f6z konusu g\u00f6r\u00fcnt\u00fcy\u00fc daha sonra hat\u0131rlama olas\u0131l\u0131\u011f\u0131 artt\u0131. Bu durum, \u00f6zelle\u015fmi\u015f sinirsel tepkilerin g\u00fcc\u00fcn\u00fcn hangi deneyimlerin haf\u0131zada eri\u015filebilir kalaca\u011f\u0131n\u0131 \u00f6ng\u00f6rmeye yard\u0131mc\u0131 oldu\u011funa i\u015faret ediyor.<\/p>\n
\n\tDr. Ueli Rutishauser konuya ili\u015fkin de\u011ferlendirmesinde, “Sonu\u00e7lar\u0131m\u0131z, amigdaladaki belirli n\u00f6ron t\u00fcrlerinin aktivitesinin, ki\u015fi bir g\u00f6r\u00fcnt\u00fcy\u00fc ilk kez g\u00f6rd\u00fc\u011f\u00fc s\u0131rada o g\u00f6r\u00fcnt\u00fcn\u00fcn daha sonra hat\u0131rlan\u0131p hat\u0131rlanmayaca\u011f\u0131n\u0131 \u00f6ng\u00f6rd\u00fc\u011f\u00fcn\u00fc ortaya koyuyor” ifadelerini kulland\u0131.<\/p>\n
\n\tAn\u0131lar olu\u015furken tekil n\u00f6ronlar takip edildi<\/h2>\n
\n\tBilim insanlar\u0131, beynin depolamak \u00fczere bilgileri nas\u0131l se\u00e7ti\u011fini ara\u015ft\u0131rmak i\u00e7in epilepsi n\u00f6betlerini izlemek amac\u0131yla beyinlerine elektrot yerle\u015ftirilen 112 hastan\u0131n kay\u0131tlar\u0131n\u0131 analiz etti. Bu elektrotlar, kat\u0131l\u0131mc\u0131lar daha \u00f6nce g\u00f6rmedikleri g\u00f6r\u00fcnt\u00fclere bakarken ara\u015ft\u0131rmac\u0131lar\u0131n tekil n\u00f6ronlar\u0131n elektriksel aktivitesini \u00f6l\u00e7mesine olanak tan\u0131d\u0131.<\/p>\n
\n\tAyn\u0131 g\u00fcn\u00fcn ilerleyen saatlerinde kat\u0131l\u0131mc\u0131lardan g\u00f6rd\u00fckleri resimleri hat\u0131rlamalar\u0131 istendi. Ara\u015ft\u0131rmac\u0131lar, kat\u0131l\u0131mc\u0131lar\u0131n haf\u0131za performans\u0131n\u0131 daha \u00f6nceki sinirsel kay\u0131tlarla kar\u015f\u0131la\u015ft\u0131rarak ba\u015far\u0131l\u0131 hat\u0131rlamayla ili\u015fkili amigdala aktivite \u00f6r\u00fcnt\u00fclerini belirledi. Bulgular iki ayr\u0131 veri setinde tekrarlanarak bu n\u00f6ronlar ile haf\u0131za olu\u015fumu aras\u0131ndaki ili\u015fkiye dair kan\u0131tlar\u0131 g\u00fc\u00e7lendirdi.<\/p>\n
\n\tTekil n\u00f6ron kay\u0131tlar\u0131ndan olu\u015fan bu al\u0131\u015f\u0131lmad\u0131k derecede geni\u015f veri koleksiyonu, Cedars-Sinai \u00f6nc\u00fcl\u00fc\u011f\u00fcndeki \u00e7ok kurumlu bir ara\u015ft\u0131rma konsorsiyumu arac\u0131l\u0131\u011f\u0131yla ve ABD Ulusal Sa\u011fl\u0131k Enstit\u00fclerinin (NIH) Yenilik\u00e7i N\u00f6roteknolojilerin Geli\u015ftirilmesi Yoluyla Beyin Ara\u015ft\u0131rmalar\u0131 (BRAIN) giri\u015fiminin deste\u011fiyle bir araya getirildi. \u00c7al\u0131\u015fman\u0131n ba\u015fyazar\u0131 olan Dr. Jiayang Xiao ara\u015ft\u0131rmaya liderlik etti.<\/p>\n
\n\tNIH program yetkilisi Dr. Mauricio Rangel-Gomez, “Bu \u00e7al\u0131\u015fma, genellikle duygusal tepkilerle ili\u015fkilendirilen insan amigdalas\u0131n\u0131n hangi deneyim ve uyaranlar\u0131n kal\u0131c\u0131 epizodik an\u0131lara d\u00f6n\u00fc\u015fece\u011fini belirlemedeki rol\u00fcne dair mekanik bir bak\u0131\u015f a\u00e7\u0131s\u0131 sunan etkili bir ara\u015ft\u0131rma niteli\u011fi ta\u015f\u0131yor. Yeni nesil ara\u00e7lar\u0131n kullan\u0131ld\u0131\u011f\u0131 bu titiz insan sinirbilimi \u00e7al\u0131\u015fmas\u0131, ke\u015ffi \u00f6l\u00e7\u00fclebilir sa\u011fl\u0131k etkilerine d\u00f6n\u00fc\u015ft\u00fcrme konusunda y\u00fcksek bir potansiyele sahip” dedi.<\/p>\n
\n\tAmigdala haf\u0131za tedavileri i\u00e7in yeni bir hedef olabilir mi?<\/h2>\n
\n\tElde edilen sonu\u00e7lar, amigdala aktivitesindeki bozulmalar\u0131n n\u00f6rolojik rahats\u0131zl\u0131klarla ili\u015fkili haf\u0131za g\u00fc\u00e7l\u00fcklerine katk\u0131da bulunabilece\u011fi ihtimalini g\u00fcndeme getiriyor. Kay\u0131tlar n\u00f6ronal tepkiler ile daha sonraki hat\u0131rlama aras\u0131nda bir ili\u015fki oldu\u011funu ortaya koysa da bu tepkileri de\u011fi\u015ftirmenin haf\u0131zay\u0131 iyile\u015ftirip iyile\u015ftiremeyece\u011fini belirlemek i\u00e7in daha fazla ara\u015ft\u0131rmaya ihtiya\u00e7 duyuluyor.<\/p>\n
\n\tAyn\u0131 zamanda beyin ve sinir cerrahisi profes\u00f6r\u00fc olan Rutishauser, “Bulgular\u0131m\u0131z \u00f6nemli klinik sonu\u00e7lar bar\u0131nd\u0131r\u0131yor; \u00e7\u00fcnk\u00fc Alzheimer hastal\u0131\u011f\u0131 ve temporal lob epilepsisi gibi bozukluklarda g\u00f6r\u00fclen haf\u0131za kay\u0131plar\u0131 k\u0131smen amigdala i\u00e7indeki bozulmu\u015f s\u00fcre\u00e7lerden kaynaklan\u0131yor olabilir. Bu nedenle amigdala, n\u00f6romod\u00fclasyon veya h\u00fccresel tedaviler kullan\u0131larak bu bozukluklar\u0131n tedavi edilmesinde uygun bir yeni hedef haline gelebilir” diye konu\u015ftu.<\/p>\n
\n\tAra\u015ft\u0131rmac\u0131lar\u0131n yan\u0131t arad\u0131\u011f\u0131 bir di\u011fer soru ise ayn\u0131 haf\u0131za se\u00e7me s\u00fcrecinin farkl\u0131 duyular i\u00e7in de ge\u00e7erli olup olmad\u0131\u011f\u0131 \u00fczerine yo\u011funla\u015f\u0131yor. Mevcut deneylerin g\u00f6rsel bilgilere odakland\u0131\u011f\u0131n\u0131 belirten Rutishauser, gelecekteki \u00e7al\u0131\u015fmalar\u0131n amigdalas\u0131n\u0131n hangi seslerin ve kokular\u0131n kal\u0131c\u0131 an\u0131lara d\u00f6n\u00fc\u015fece\u011fini belirlemeye de yard\u0131mc\u0131 olup olmad\u0131\u011f\u0131n\u0131 inceleyebilece\u011fini s\u00f6zlerine ekledi.<\/p>\n<\/p><\/div>\n","protected":false},"excerpt":{"rendered":"
Beyin her g\u00fcn say\u0131s\u0131z g\u00f6r\u00fcnt\u00fc ve deneyimi kaydediyor ancak bunlar\u0131n yaln\u0131zca k\u00fc\u00e7\u00fck bir k\u0131sm\u0131 kal\u0131c\u0131 an\u0131lara d\u00f6n\u00fc\u015f\u00fcyor.
Bilim insanlar\u0131, neyin hat\u0131rlanaca\u011f\u0131n\u0131 tahmin etmeye yard\u0131mc\u0131 olan bir sinirsel aktivite \u00f6r\u00fcnt\u00fcs\u00fc tespit ederek geleneksel olarak duygular ve korkuyla ili\u015fkilendirilen bir beyin b\u00f6lgesinin \u00e7ok daha geni\u015f bir i\u015flevi oldu\u011funa i\u015faret etti.
Cedars-Sinai Sa\u011fl\u0131k Bilimleri \u00dcniversitesindeki […]<\/p>\n","protected":false},"author":1,"featured_media":46628,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4,5],"tags":[],"class_list":["post-76131","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genel","category-gundem"],"yoast_head":"\n
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Bilim insanlar\u0131 ke\u015ffetti - Milli Haber","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/millihaber.com.tr\/?p=76131","og_locale":"tr_TR","og_type":"article","og_title":"Neyi hat\u0131rlayaca\u011f\u0131m\u0131za nas\u0131l karar veriyoruz? Bilim insanlar\u0131 ke\u015ffetti - Milli Haber","og_description":"
Beyin her g\u00fcn say\u0131s\u0131z g\u00f6r\u00fcnt\u00fc ve deneyimi kaydediyor ancak bunlar\u0131n yaln\u0131zca k\u00fc\u00e7\u00fck bir k\u0131sm\u0131 kal\u0131c\u0131 an\u0131lara d\u00f6n\u00fc\u015f\u00fcyor.
Bilim insanlar\u0131, neyin hat\u0131rlanaca\u011f\u0131n\u0131 tahmin etmeye yard\u0131mc\u0131 olan bir sinirsel aktivite \u00f6r\u00fcnt\u00fcs\u00fc tespit ederek geleneksel olarak duygular ve korkuyla ili\u015fkilendirilen bir beyin b\u00f6lgesinin \u00e7ok daha geni\u015f bir i\u015flevi oldu\u011funa i\u015faret etti.
Cedars-Sinai Sa\u011fl\u0131k Bilimleri \u00dcniversitesindeki […]","og_url":"https:\/\/millihaber.com.tr\/?p=76131","og_site_name":"Milli Haber","article_published_time":"2026-11-13T04:34:13+00:00","og_image":[{"url":"https:\/\/trthaberstatic.cdn.wp.trt.com.tr\/resimler\/2120000\/beyin-2120635.jpg","type":"","width":"","height":""}],"author":"admins","twitter_card":"summary_large_image","twitter_misc":{"Yazan:":"admins","Tahmini okuma s\u00fcresi":"4 dakika"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/millihaber.com.tr\/?p=76131#article","isPartOf":{"@id":"https:\/\/millihaber.com.tr\/?p=76131"},"author":{"name":"admins","@id":"https:\/\/millihaber.com.tr\/#\/schema\/person\/ce25ff78bd50c3fcd185fb298962da20"},"headline":"Neyi hat\u0131rlayaca\u011f\u0131m\u0131za nas\u0131l karar veriyoruz? 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